PAIN MANAGEMENT

Ksgaba Nt 100

Gabapentine 100 mg Nortryptline 10 mg Tablets

Introduction

Gabapentine + Nortriptyline is a combination medicine used for the management of neuropathic pain, a chronic nerve disorder characterized by shooting, burning, stabbing pain, spontaneous unprovoked pain, evoked pain, and disturbed sleep patterns.

Mechanism of Action
  • Gabapentine: Binds to specific sites on voltage-gated calcium channels, helping to reduce nerve excitability and relieve pain.
  • Nortriptyline: A tricyclic antidepressant that prolongs the action of serotonin and noradrenaline by preventing their reabsorption into neurons, thereby blocking pain signal transmission in the brain.
Uses

Treatment of neuropathic pain (chronic nerve pain)

Medicinal Benefits
  • Gabapentine + Nortriptyline works synergistically:
  • Gabapentine eases nerve pain and lowers seizure risk.
  • Nortriptyline enhances mood-regulating neurotransmitters and disrupts pain pathways in the central nervous system.
  • Together, they offer enhanced relief from neuropathic symptoms and improve quality of life.
Dosage and Administration
  • Take with or without food, as directed by your healthcare provider.
  • Swallow tablets whole with a glass of water; do not chew or break.
  • Maintain consistent timing each day for optimal benefits.
  • Do not stop the medication abruptly without consulting your doctor.
Storage

Store in a cool, dry place away from sunlight and moisture.

Warnings
  • Use caution while driving or operating machinery as this medication may cause drowsiness or dizziness.
  • Avoid alcohol consumption, which may increase side effects like sleepiness and dizziness.
  • Inform your doctor if you are pregnant, breastfeeding, or planning pregnancy.
  • Not recommended for children unless specifically prescribed.
Precautions

Discuss your complete medical history, especially if you have:

  • Kidney or liver problems
  • Respiratory issues
  • History of mood disorders or depression
Common Side Effects
  • Dizziness
  • Sleepiness
  • Tiredness
  • Headache
  • Nausea and vomiting
  • Blurred vision
  • Dry mouth
  • Tingling sensations
Word of Advice
  • Do not skip doses even if you feel better; complete the full course.
  • Stay hydrated and avoid alcohol while on this medication.
  • Consult your healthcare provider immediately if side effects worsen or new symptoms appear.
  • Regular follow-ups are important to monitor your progress and adjust the dosage if needed.